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Another larger study on Vitamin D and Covid


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#1 K Wave

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Posted 14 May 2020 - 12:13 AM

https://papers.ssrn....ract_id=3585561

 

Some pretty shocking numbers in relation to Vitamin D deficiency vs normal  levels in hospitalized Covid patients

 

Patients that had Vitamin D deficency, 99% died. Vast majority also had comorbidities which likely contributed to the deficiency.

 

Those with normal levels, despite 18% with comorbidities, only 4% died. (likely mostly ones with comorbidities).

 

And once you even go into insufficiency, things turn south in a hurry.

 

It sure looks like people with any comorbidities should go out of their way to get their serum D level checked and take any required steps to get any deficiencies corrected ASAP.

 

 

table.png


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#2 OEXCHAOS

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Posted 14 May 2020 - 07:42 AM

Basically the same as this smaller study.
https://poseidon01.s...5Xw774Dwa9kgkGo


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#3 typicalbear

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Posted 14 May 2020 - 08:29 AM

Having a revved up immune system is exactly the opposite of what people with autoimmune problems want. 



#4 K Wave

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Posted 14 May 2020 - 08:35 AM

Having a revved up immune system is exactly the opposite of what people with autoimmune problems want. 

Not sure what specific autoimmune disorders you are talking about, but Vitamin D is well known as having a beneficial preventative effect on cytokine storms.

 

Here is just one of many.

https://www.ncbi.nlm...pubmed/25331710


The strength of Government lies in the people's ignorance, and the Government knows this, and will therefore always oppose true enlightenment. - Leo Tolstoy

 

 


#5 K Wave

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Posted 14 May 2020 - 08:38 AM

Basically the same as this smaller study.
https://poseidon01.s...5Xw774Dwa9kgkGo

Yep, certainly appears that folks should betting getting out of the house everyday now that spring is here.

Been saying this until blue in the face...staying inside worrying is about the worst thing you can do for your physical and mental health.

 

The vast majority of USA is Vitamin D insufficient to deficient for much of the year.
https://www.ncbi.nlm...les/PMC3782116/

In the Midwest at latitude 40°, serum 25OHD increases by 50% from 20 to 30 ng/mL in summer; this change is equivalent to a daily oral vitamin D dose of 2000 IU daily. The UV spectrum is effective only when the sun is more than 30° above the horizon. Below that level, ground pollution filters out the UV rays. In the Midwestern section of North America, effective UV light occurs only between late April and early September. Effective UV exposure time is 2 months less in Canada and 2 months more in Florida. Vitamin D supplementation should be increased in winter.

 

When this data becomes widely known, Florida real estate should boom! laugh.png
Florida doing stunningly better than the Northeast during this outbreak by the way, despite a huge elderly population, and multiple large population centers. (#8 in population density, right behind NY at #7)
NY and NJ have 15 times the death rate per mil as FL.

 


Edited by K Wave, 14 May 2020 - 08:39 AM.

The strength of Government lies in the people's ignorance, and the Government knows this, and will therefore always oppose true enlightenment. - Leo Tolstoy

 

 


#6 typicalbear

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Posted 14 May 2020 - 08:56 AM

 

Having a revved up immune system is exactly the opposite of what people with autoimmune problems want. 

Not sure what specific autoimmune disorders you are talking about, but Vitamin D is well known as having a beneficial preventative effect on cytokine storms.

 

Here is just one of many.

https://www.ncbi.nlm...pubmed/25331710

 

 

RA



#7 gannman

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Posted 14 May 2020 - 09:01 AM

we take 2000 iu a day imo it definitely boosts immunity


feeling mellow with the yellow metal


#8 K Wave

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Posted 14 May 2020 - 09:17 AM

 

 

Having a revved up immune system is exactly the opposite of what people with autoimmune problems want. 

Not sure what specific autoimmune disorders you are talking about, but Vitamin D is well known as having a beneficial preventative effect on cytokine storms.

 

Here is just one of many.

https://www.ncbi.nlm...pubmed/25331710

 

 

RA

 

 

Vitamin D deficiency has been linked, not necessarily the cause. Sounds like it might help though.

 

https://www.ncbi.nlm...les/PMC3539179/

Conclusion:

It appears that vitamin D deficiency is highly prevalent in patients with RA, and that vitamin D deficiency may be linked to disease severity in RA. As vitamin D deficiency has been linked to diffuse musculoskeletal pain, these results have therapeutic implications. Vitamin D supplementation may be needed both for the prevention of osteoporosis as well as for pain relief in patients with RA.

 

Another

https://www.healthli...-to-vitamin-d#3

 

“Vitamin D deficiency is associated with the clinical activity of the disease,” the authors wrote. “The quantification of serum 25 (OH) D levels and, consequently, vitamin D supplementation, should be considered in the management of patients with RA.”

While this is the first study to look into how a person’s vitamin D levels could impact the course of a person’s RA treatment, the link between vitamin D and the condition is well known, said Dr. Daniel Small, a rheumatologist at Mayo Clinic.

 

Small said that anyone who has an autoimmune disease, like RA, osteopenia, or osteoporosis and neurological disorders should make sure to get their vitamin D levels checked.

 

And this one which also associates Vitamin D with RA, but says once RA has set in, another approach other than simple D supplementation may be needed due to a sort of Vitamin D desensitivity.

https://www.medicaln...inflamed-joints

 

Although the study was limited to investigating cells in the laboratory, the findings would appear to support the idea that maintaining vitamin D levels might help to prevent rheumatoid arthritis and other inflammatory diseases.

However, they would also suggest that simply taking vitamin D supplements is unlikely to help people with rheumatoid arthritis because their immune cells are already desensitized.

“Instead,” notes study co-author Dr. Louisa Jeffery, also from the University of Birmingham, “much higher doses of vitamin D may be needed, or possibly a new treatment that bypasses or corrects the vitamin D insensitivity of immune cells within the joint.”

The researchers now want to take the research further and find out why rheumatoid arthritis causes immune cells to become insensitive to vitamin D, and how this might be prevented. They also want to find out if there are similar effects in other inflammatory conditions.

 

It could also be that it might just take time to sensitivity to come back once the deficiency is erased....kind of like how folks can reverse adult onset diabetes if they have the willpower to shed their bad food choices.

In any event, it sounds like extra Vitamin D would not hurt any, and might help. And if you are getting the D by being out in the sun exercising, might help even more, with a bit of synergism.


Edited by K Wave, 14 May 2020 - 09:17 AM.

The strength of Government lies in the people's ignorance, and the Government knows this, and will therefore always oppose true enlightenment. - Leo Tolstoy

 

 


#9 K Wave

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Posted 14 May 2020 - 09:37 AM

NJ and Puerto Rico another interesting comparison..

 

Both have extremely high density NJ at 1210 per sq. mi. and PR at 1056 per sq mi.

 

NJ 1095 deaths per mil, PR 35, over 30X difference.


The strength of Government lies in the people's ignorance, and the Government knows this, and will therefore always oppose true enlightenment. - Leo Tolstoy

 

 


#10 OEXCHAOS

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Posted 14 May 2020 - 09:41 AM

 

Basically the same as this smaller study.
https://poseidon01.s...5Xw774Dwa9kgkGo


When this data becomes widely known, Florida real estate should boom! laugh.png
Florida doing stunningly better than the Northeast during this outbreak by the way, despite a huge elderly population, and multiple large population centers. (#8 in population density, right behind NY at #7)
NY and NJ have 15 times the death rate per mil as FL.

 

 

I was just looking at that. I was willing to give the nursing homes and maybe even health policy folks some credit, but deep down, I'm thinking it's largely the sun!


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