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Quarantine may doom a future generation


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#1 Rogerdodger

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Posted 27 May 2020 - 10:27 PM

Early exposure to virus may save future lives in a way similar to early exposure to peanuts may prevent nut allergy.

"A trial, involving hundreds of babies under a year old at high risk for developing peanut allergy, established that kids could be protected by regularly eating a popular peanut butter-flavored Israeli snack called Bamba. A follow-up study later showed those kids remained allergy-free even after avoiding peanuts for a year.

 

Did improvements in sanitation doom the kids in the 1950's to the Polio epidemic by preventing early exposure to the virus?

Will this Quarantine likewise doom a future generation to another pandemic?

 

From:

The man in the iron lung
"When he was six, Paul Alexander contracted polio and was paralyzed for life. Today he is 74, and one of the last people in the world still using an iron lung. But after surviving one deadly outbreak, he did not expect to find himself threatened by another."

Polio existed in isolated outbreaks around the world for millennia, but it didn’t become epidemic until the 20th century – helped, ironically, by improvements in sanitation.

Poliovirus enters the body through the mouth, via food or water, or unwashed hands, contaminated with infected fecal matter. Until the 19th century, almost all children would have come in contact with poliovirus before the age of one, while they still enjoyed protection from maternal antibodies transferred from mother to baby during pregnancy. However, as sanitation improved, children were less likely to come into contact with poliovirus as babies; when they encountered it as older children, their immune systems were unprepared.
There was no way of predicting who would walk away from an infection with a headache, and who would never walk again.

In most cases, the disease had no discernible effect.

Of the 30% or so who showed symptoms, most experienced only minor illness.

But a small proportion, 4-5%, exhibited serious symptoms, including extreme muscular pain, high fever and delirium. As the virus hacked its way through the neural tissue of the spinal cord, a few of those infected were paralyzed.
This progression of the virus was known as paralytic polio. Roughly 5-10% of patients who caught paralytic polio died, although this number was far higher in the days before widespread use of the iron lung.


Edited by Rogerdodger, 27 May 2020 - 10:35 PM.


#2 12SPX

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Posted 28 May 2020 - 07:51 AM

Thanks, very interesting great to learn stuff like that!! 



#3 pdx5

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Posted 28 May 2020 - 09:16 AM

Living proof of what RD said is in observing what is happening in India, a country 1/3 size of United States (US) in land area, and 4 times bigger population. In other words, for those living in Rio Linda, India is 12 times more densely populated than US. Forget social distancing! So why so few have died from covid-19 in India compared to US? 

 

I grew up there and spent my first 20 years of life there. It is much more dirty place than US. It is a virus infested place. Sanitation was very bad during my years there. I doubt if it has improved by orders of magnitude at the current time. I had small pox at age 8 in Mumbai. Still have marks left on my face from that disease. I can only conclude Indians must develop large dose of immunity just to survive there. I hope after living in US for 60 years I still carry some anti-bodies streaming through my blood vessels.


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#4 Rogerdodger

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Posted 28 May 2020 - 09:19 AM

Asymptomatic cases may be more common than suspected...

 

"The first study, published in JAMA Network Open, found that 42 percent of cases from a group of people in Wuhan, China, were asymptomatic. The second study, published in Thorax, found much higher rates of asymptomatic individuals: 81 percent of cases on a cruise to Antarctica."

 

Building immunity for the next generation?


Edited by Rogerdodger, 28 May 2020 - 09:22 AM.