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Skin cancer: Half now survive advanced melanoma


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#1 Rogerdodger

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Posted 28 September 2019 - 09:45 AM

Skin cancer: Half now survive advanced melanoma

Sept. 28, 2019
There were 945 patients in the trial, a third were given nivolumab, a third were given ipilimumab and a third were given both.
Doctors then looked at the five-year survival rate - the proportion of patients still alive after five years.
The results showed:
    26% were still alive on ipilimumab alone
    44% were still alive on nivolumab alone
    and 52% were still alive when given both.

Ipilimumab and nivolumab both stop some cancers from hiding and allow the immune system to attack.
They interrupt the chemical signals that cancers use to put the brakes on the immune system.
Nivolumab blocks the off-switch on white blood cells called PD-1. Ipilimumab blocks a similar switch called CTLA-4.
It is described as taking the brakes off the immune system.
"By giving these drugs together you are effectively taking two brakes off the immune system rather than one so that the immune system is able to recognise tumours it wasn't previously recognising and react to that and destroy them," Prof Larkin said.
Earlier results from this trial led to these drugs being made available around the world - including on the UK's National Health Service.
The decision to approve the drugs for melanoma was one of the fastest in NHS history.
And they are also being used in other cancers such as lung and kidney.



#2 hhh

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Posted 28 September 2019 - 10:04 AM

I would use cannabis oil. It cured a dark tumour-like blob on my cat's nose in a few weeks and a friend's skin tumour as well.