Just put out. Geert in a as plain of english as he can do.
The how and why of what he thinks is coming.
https://www.voicefor...le-of-pandemics
Vicious circle has been most likely unleashed from this folly, as he thinks we have now hit pretty much full Antibody Dependent Enhancement of Infection.
He warned warned warned them not to do Antigen Specific priming during a pandemic.
some snippets - see if it rings any kind of bell about the current state of Omicron...
Suboptimal population-level immune pressure becomes even more worrisome when the circulating virus is a viral variant (i.e., different from the viral lineage that originally primed the population). This will drive natural selection of more infectious immune escape variants that will eventually adapt to the population because they’ve gained a competitive replication advantage.
When that happens, the variant becomes dominant. Of course, increased viral infection rates will result in increased progeny of mutants; this will expedite the selection of appropriate variant(s) to overcome the suboptimal immune pressure exerted on their life cycle. When ‘more infectious’ variants begin to dominate, the likelihood for previously asymptomatically infected people to become re-exposed will augment.
As a result of previous asymptomatic infection some of them may have developed short-lived titers of antigen(Ag)-specific, non-neutralizing antibodies (Abs). Non-neutralizing Abs can, however, enhance viral infectiousness if they bind in sufficient quantities to the virus (so-called Ab-dependent enhancement of infection; ADEI). However, the chance for a re-infection to occur shortly after primary infection is normally low unless the virus is very infectious or highly concentrated, or the cell-based innate immune system (CBIIS) is weakened (worst case scenario exists in densely populated areas with poor hygiene conditions and inadequate nutrition).
In case ADEI occurs, the infection rate in the population will increase. This makes it now more likely for the virus to break through the cellular innate immune defense and trigger the adaptive immune system.
Due to ‘antigenic sin’, adaptive immune triggering will, however, first recall the ‘old’ Ag-specific Abs (i.e., those that were acquired as a result of the original immune priming). Although these antibodies will be recalled rapidly and in large quantities (because of immunologic memory!), they will not do well at recognizing the dominantly circulating ‘more infectious’ variant.
Consequently, the neutralizing capacity of these Abs will diminish. This increasingly enables non-neutralizing Abs to bind to the virus, and thereby promotes an even more pronounced ADEI effect. The more infectious the dominant variant becomes, the more strongly and frequently the virus will break through the host’s innate immune defense. Simultaneously, titers of antigen(Ag)-specific Abs will continue to rise and their neutralizing capacity continue to diminish. This will result in an increased likelihood for ADEI to occur and a higher susceptibility of the population to re-infection.
Consequently, vaccinees pave the way for pandemics of viruses they asymptomatically shed/ transmit. By preventing trans infection, virulence-neutralizing Abs increase viral uptake by antigen-presenting cells (APCs) and thereby enable activation of poorly MHC class I-restricted CD8+ T cells that will not only kill host cells infected by the virus that is responsible for initiation of this cascade of immune events, but also host cells infected by other immunogenically related viruses (i.e., presenting the same CTL epitope on cell surface-expressed MHC class I molecules upon their internalization into APCs: e.g., common cold CoV, influenza virus, poxvirus, RSV).
However, the immune pressure exerted on viral virulence is only suboptimal as it cannot prevent productive infection. Nature will, therefore, proceed with natural selection and adaptation of viral immune escape variants that can overcome this immune pressure (see fig. 1; the molecular details of the SC-2 immune escape variants that I predict to be selected are described in)
And a new warning based on the current trending hype of MonkeyPox and Avian Flu:
Based on all the above, you should not fall into the trap of getting yourself vaccinated against monkeypox, avian flu or even seasonal flu virus with non-replicating vaccines
